# FDA Approves Methapharm Inc.'s PROVOCHOLINE for Respiratory Testing Methapharm Inc. received FDA approval for PROVOCHOLINE (methacholine chloride), an inhaled diagnostic agent used to assess bronchial hyperresponsiveness in patients with suspected asthma, establishing a specialized niche in the pulmonary diagnostics market. The approval positions Methapharm as a key supplier of bronchial challenge testing solutions, a procedure that has become standard in asthma diagnosis and management protocols.