United Therapeutics Corporation (NASDAQ: UTHR) shares experienced a significant increase, rising 14.1% to $541.10 during midday trading on Wednesday. The stock led gains within the Russell 1000 index, outperforming the broader market.

Despite the sharp rally, the source text indicates that no confirmed company-specific catalyst was found to explain the move. The stock's performance occurred alongside a broader market rally driven by softer-than-expected inflation data.

On the economic front, the Personal Consumption Expenditures (PCE) price index rose 0.3% in August, with the annual rate slowing to 3.4% versus a forecast of 3.7%. This cooler inflation data contributed to a decline in the probability of a Federal Reserve rate hike in October, which traders now price in at less than 40%.

United Therapeutics' surge came as technology and software sectors led the S&P 500 higher. The S&P 500 advanced 0.6% to 7,717, while the Nasdaq 100 rose 0.9% to 30,605.