Establishment Labs Holdings Inc. (the “Company”) has entered into Amendment No. 3 to its Master Supply Agreement with NuSil Technology LLC. The amendment, effective January 1, 2027, was executed on October 14, 2026, by the Company through its wholly owned subsidiary, Establishment Labs, S.A. (ELSA).

The primary purpose of Amendment No. 3 is to extend the duration of the existing supply agreement. The initial term of the Agreement, which previously was set to expire on December 31, 2026, has been extended to December 31, 2031.

In addition to the extended term, the amendment modifies specific provisions of the original contract. These changes relate to NuSil’s manufacturing and sale of medical-grade silicone for use in specified ELSA products. The amendment also adjusts terms regarding payments, business continuity, and certain intellectual property and pricing provisions.

The agreement includes an automatic renewal clause. If neither party provides written notice by December 31 of the year prior to the expiration of the initial term or the then-current renewal term, the agreement will renew for successive one-year terms for up to five additional renewal periods.

A copy of Amendment No. 3 is filed as Exhibit 10.1 to this report and is incorporated by reference.