CNBX Pharmaceuticals Inc. has reported a change in its independent registered public accounting firm. The company’s Board of Directors dismissed Elkana Amitai CPA, effective September 28, 2026. The Board made this decision on the same date, acting under its delegated authority.

On September 28, 2026, the Board engaged Vilki & Co. as the new independent accounting firm. Vilki & Co. is located at Luxor Palace, Gandhi Smruti Bhavan, Gujarat, India, with the postal code 394651. The new firm will serve as the independent accountant for the fiscal year ended August 31, 2026.

The filing states that the change was not the result of any disagreement with the Former Accounting Firm. Elkana Amitai CPA’s audit reports for the fiscal years ended August 31, 2024, and August 31, 2025, did not contain an adverse opinion or disclaimer of opinion. However, those reports included an explanatory paragraph indicating substantial doubt about the company’s ability to continue as a going concern.

The company confirms that there were no disagreements with Elkana Amitai CPA regarding accounting principles, financial statement disclosure, or auditing scope during the years ended August 31, 2025, and 2026. Additionally, there were no reportable events as defined in Regulation S-K.

CNBX Pharmaceuticals has requested that Elkana Amitai CPA provide a letter to the Securities and Exchange Commission confirming the accuracy of the statements made in this filing. A copy of that letter is attached as Exhibit 16.1.